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Detection Medhodologies Of Covid-19 | Testings | New techs | Wit Biology

                          Detection Medhodologies Of Covid-19



     Where are we right now with testing well. We've come an extended way and that we still have an extended thanks to go where we are immediately is we are ready to had best over 100 thousand tests per day on Americans which is sufficient to check the high priority individuals those that are within the hospital those that are sick health care workers people in long-term care facilities first responders who are symptomatic.



      We aren't at a state nor will we be at a state within the near future where anyone who just wants a test or those that are mildly ill can get a test. We have many thousands each day within the next couple weeks, we'll not have millions per day so we've sufficient testing to try to to what we'd like to do to affect patient care and to stay people safe. But it's getting to be a couple of weeks before we're beyond that time Abbott has begin with a with a rapid test - you are doing a nasal swab and you recognize within 5 to 13 minutes. Whether you're positive is there any role for that I mean not generally is there any role for that.

    But is there any role for that in augmenting the speed of knowing who has this and broadening who can get the test as long as they assert they will do 50,000 tests a day. Now the Abbott point of care test really vital and as you acknowledged it's it's one among the sole only a couple of tests and clearly the most disseminated which will get a positive result within four minutes and a negative result within 50 minutes.

    Now they go to supply 50,000 tests each day and that is tons . But it's not five hundred thousand or five million. So what we're doing with this test is we might hope that those that actually need an instantaneous result either for a clinical reason to travel on a study protocol to understand whether they're isolated within the ICU can get this type of tests also as individuals in vital epidemiologic investigations.

    For example, a home we all know that home mortality are often 30, 40, 50 percent. So it's extremely important to identify test people both to guard our seniors but also to understand what seniors could be ill and may spread it so until this could be many hundreds of thousands per day. This is still a limited and really precious resource because we will get a result essentially immediately and there is no other test which will do this.

    I want to modify back to the difficulty of how we test you gave me a notice of the thought that we were gonna have swabs that that would be self administered in other words nasal swabs that CDC was testing versus the more aggressive nasopharyngeal swab. Can you walk me through that how are we getting to change how we're getting to approach testing swab wise so as to decrease the necessity for PPE at a time.

    When we need it within the hospital's you're exactly one hundred pc correct the self swab really are some things that may not it is a critical breakthrough because as you pointed out it doesn't got to be administered by a healthcare provider just like the nasopharyngeal swabs and when that healthcare provider does a nasopharyngeal swab they need to vary PPE between each test and the exact fact is we calculated this early on is that if we really wanted to have widespread testing consistent with the capability that we had even two weeks ago.

    We would have blown eighty percent as a strategic national stockpile within the first fortnight just on testing and clearly that's unconscionable. Because people need the PPE within the hospitals. So this nasal swab was so important to me and to our teams and United Health Group out on the West Coast with the Gates Foundation really did the validation study to undergo the FDA it allows at the community based testing, which you recognize may be a bit invasive and there is no PPE. So we expect this is often really important to subsequent phase of testing.

    The Immunological testing something we call analyzer which is an exciting test it's an immunoassay. I wanted you to speak to what the goal of that might be in terms of knowing whose immune maybe knowing who features a recent infection. If it's an IgM what walk me through how that test would be useful to us immediately . So first of all we're still working to finalize the concepts of how this is able to be used , but this is often the working hypothesis kind of right off the press.

    We for epidemiologic reasons we'd like to understand what percentage people were infected and you cannot really know that because there are numerous asymptomatic infections that albeit we had all the tests that we could people wouldn't come to be tested and you cannot test 300 million people the second important component is it might be really fantastic to possess kind of a digital immunity passport that would be protected health information that you simply can carry that.

    For example if you are a healthcare worker during a long-term facility that we all know wherever you go you're certified immune right and if this test can show that you simply have IgG and as we expect that the IgG will correlate with immunity which must be absolutely proven right that, if you've got an IgG you are not shedding virus and we're performing on that immediately . But if you had that then essentially we might know that for instance you'll not contract the virus and spread it to future care facilities or the elderly does one see some extent of care.

    Where you've got the the the PCR test then you've got the the serological tests. One for active infection, the opposite one for you recognize antibodies to took over nineteen. I think we'll have extremely popular very user-friendly quote bioassay like abilities which will be done within a few of minutes to point out your immunity. We will have point-of-care testing to point out if you're infected currently in shedding virus again not so scalable consider the Abbott Machine fifty thousand each day not five million each day and within the future we'll have a vaccine that you simply know is twelve to eighteen months away.

    So are you recognize this looks good coming together and it's gonna close soon, but it isn't together now you recognize this is often a fresh virus the world has never seen with unforeseen challenges and you recognize immediately . We are focused on ensuring that folks who need testing who have a difference in their therapies or could transmit the virus to needy populations all get tested.

    We can do this we cannot do tons quite that and that i want people to be realistic that we've come an extended way but that's where we are in secondly ensuring , we meet the clinical needs with ventilators hydroxychloroquine all the type of things which will save lives today tomorrow and over subsequent couple of weeks. But subsequent station we just talked about is coming very soon.

    Do you think we will transition as a society to using testing to some extent to either augment or to exchange the necessity for isolation, so in fact you're 100% correct and this is a difficult question but I think the answer is yes. This is not an on or off switch right we're not getting to be within the middle of the pandemic then we're getting to be out of the pandemic completely. There was getting to be transition times on the country doesn't open up doesn't closed down and open up all with the sunshine switch. It is clear that we're getting to got to get critical industries including healthcare industries back on their feet and back working and through that transition outing of this or potentially into the next wave.

    We are getting to need a mixture of serologic testing for immunity plus active testing to for those that are asymptomatic thereon that you simply know it's messy, it's not clean, it isn't perfect, it isn't black and white. But that is reality right. Life biology medicine isn't so simple so I accept as true with you completely during the transition out of this and potentially during the transition into a next phase that kind of combination is basically important it cannot be finished 300 million people, but certainly for healthcare workers and important industries i feel there is a combination i feel it's going to need to happen no doubt whatsoever in my mind...

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